I have tried many shareware programs but finally I found a better, cheaper, faster way to remove it. You don’t need to change or think about any acceleration curves, etc.

This is the best way to remove mouse acceleration on Mac Os X:

In your terminal(terminal is located in Applicatons/Services/Terminal):

macpro:~ user$ curl -O http://ktwit.net/code/killmouseaccel
macpro:~ user$ chmod +x killmouseaccel
macpro:~ user$ ./killmouseaccel mouse


It was copypasted from here.

I write it here just in order not to loose such a useful recipe.